5 Simple Techniques For LDN-27219 pharmacological properties
A single especially fascinating compound is LDN-27219. Although most tTG inhibitors are made to bind to your protein crosslinking Lively web-site, LDN-27219 as a substitute binds on the nucleotide binding pocket from the enzyme although it is in its shut-condition conformation, and stabilizes that conformation to prevent crosslinking activity.78 Sc